<?xml version="1.0" encoding="UTF-8"?>
<sbml xmlns="http://www.sbml.org/sbml/level2/version4" level="2" version="4">
  <model id="Model">
    <listOfUnitDefinitions>
      <unitDefinition id="time">
        <listOfUnits>
          <unit kind="second" scale="0" multiplier="60"/>
        </listOfUnits>
      </unitDefinition>
    </listOfUnitDefinitions>
    <listOfCompartments>
      <compartment id="system" name="system" size="1" constant="true"/>
    </listOfCompartments>
    <listOfSpecies>
      <species id="tetR" name="tetR" compartment="system" initialConcentration="0" hasOnlySubstanceUnits="true" boundaryCondition="false" constant="false"/>
      <species id="lacI" name="lacI" compartment="system" initialConcentration="0" hasOnlySubstanceUnits="true" boundaryCondition="false" constant="false"/>
      <species id="cIts" name="cIts" compartment="system" initialConcentration="0" hasOnlySubstanceUnits="true" boundaryCondition="false" constant="false"/>
    </listOfSpecies>
    <listOfReactions>
      <reaction id="equation_tetR" name="equation_tetR" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="tetR"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="tetR"/>
          <modifierSpeciesReference species="lacI"/>
          <modifierSpeciesReference species="cIts"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <cn type="integer"> 1 </cn>
              <apply>
                <minus/>
                <apply>
                  <divide/>
                  <cn type="integer"> 1 </cn>
                  <apply>
                    <plus/>
                    <cn type="integer"> 1 </cn>
                    <apply>
                      <exp/>
                      <apply>
                        <times/>
                        <cn type="integer"> -10 </cn>
                        <apply>
                          <plus/>
                          <cn type="integer"> 0 </cn>
                          <apply>
                            <times/>
                            <cn> -0.9 </cn>
                            <ci> lacI </ci>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
                <ci> tetR </ci>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="equation_lacI" name="equation_lacI" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="lacI"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="tetR"/>
          <modifierSpeciesReference species="lacI"/>
          <modifierSpeciesReference species="cIts"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <cn type="integer"> 1 </cn>
              <apply>
                <minus/>
                <apply>
                  <divide/>
                  <cn type="integer"> 1 </cn>
                  <apply>
                    <plus/>
                    <cn type="integer"> 1 </cn>
                    <apply>
                      <exp/>
                      <apply>
                        <times/>
                        <cn type="integer"> -10 </cn>
                        <apply>
                          <plus/>
                          <cn type="integer"> 0 </cn>
                          <apply>
                            <times/>
                            <cn> -0.8 </cn>
                            <ci> cIts </ci>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
                <ci> lacI </ci>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
      <reaction id="equation_cIts" name="equation_cIts" reversible="false" fast="false">
        <listOfProducts>
          <speciesReference species="cIts"/>
        </listOfProducts>
        <listOfModifiers>
          <modifierSpeciesReference species="tetR"/>
          <modifierSpeciesReference species="lacI"/>
          <modifierSpeciesReference species="cIts"/>
        </listOfModifiers>
        <kineticLaw>
          <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
              <times/>
              <cn type="integer"> 1 </cn>
              <apply>
                <minus/>
                <apply>
                  <divide/>
                  <cn type="integer"> 1 </cn>
                  <apply>
                    <plus/>
                    <cn type="integer"> 1 </cn>
                    <apply>
                      <exp/>
                      <apply>
                        <times/>
                        <cn type="integer"> -10 </cn>
                        <apply>
                          <plus/>
                          <cn type="integer"> 0 </cn>
                          <apply>
                            <times/>
                            <cn> -0.9 </cn>
                            <ci> tetR </ci>
                          </apply>
                        </apply>
                      </apply>
                    </apply>
                  </apply>
                </apply>
                <ci> cIts </ci>
              </apply>
            </apply>
          </math>
        </kineticLaw>
      </reaction>
    </listOfReactions>
  </model>
</sbml>



